HLA frequencies in less common arthropathies.

Frequencies of HLA-A, B and DRB1 alleles in a large normal population living in the city of Mashhad, Northeastern Iran

Objective(s): The population in Iran is a genetic admixture of the ancestral Aryan and other populations neighboring Iran. Different ethnic groups in Iran show wide regional distributions for many human leukocyte antigen (HLA) alleles. Therefore, it is necessary and sensible to study the differences in HLA allele distribution in different area. We studied the HLA class I and II allele frequenci...

Frequency of rare HLA-A allelic groups in Gilak, Lor, Kurdish and Arab ethnic groups of Iran

Abstract Background and Objectives Histocompatibility antigens (HLAs) have high genetic diversity and their frequency can be diverse in different ethnicities. Therefore, the determination of these antigens in different ethnicities can provide data used in the expansion of centers for the registration of stem cell donors. Materials and Methods In this descriptive study, donor DNA was extracted ...

Allele Frequencies of HLA-A, B and DRB1 among People of Fars Ethnicity Living in Tehran

Background: Human leukocyte antigens (HLA) are polymorphic cell surface proteins. Distribution of HLA alleles vary among different racial and ethnic populations in unrelated stem cell registries. Determination of HLA allele frequencies in different ethnic groups is useful for population genetic analyses. Materials and Methods: Based on data available from the Iranian Stem Cell Donor Registry...

Frequencies of HLA-E*01:01/*01:03 Alleles in an Iranian Healthy Population and Its Comparison with Hyperglycemia Patients

Background and Aims: The human leukocyte antigen-E (HLA-E) is a member of non-classical HLA class-I genes which is highly conserved through evolution. In general, so far 25 alleles of HLA-E have been described. However, the existence of only two allelic group; HLA-E*01:01 and HLA-E*01:03 have been demonstrated in all the populations. HLA-E*01:01 and HLA-E*01:03 differ only at codon 107 of exon ...

HLA Class I Allele Frequencies in Southern Iranian Women with Breast Cancer